There is a rumor around that you do not need a tank to do this run.  I call FALSE. If you do not have someone that can taunt on a very regualar basis, say every 10 seconds or so, you will lose clothies.  

You also need a priest, they are a must, there will be times you HAVE to shackle.

You also need a mage, they are a must, there will be times you need lots of AOE, like the green blobs in the Abomination area and the bugs in the gated area, and when your teammate walks over a trapped box.

Groupings that will work:
tank
mage
priest

and

either another priest and dps
or
2 dps

Rob