I don't like comment moderation. Of course, it helps me put abusive and offensive comments away, but I can do so from my mobile browser too. I leave comment moderation turned off so that a discussion may spark. You know, imagine of a post where ten people left comments with some valuable information that attracts and further extends the discussion. If the comment moderation is turned on, and I'm not near to the Internet to approve those comments, those ten comments will not go live and as a result the people visiting/reading the post will simply think there were no comments yet.

This way, I'm losing more comments.

It's everyone's personal choice, though. Famous bloggers often like to turn comment moderation on because either way they will be getting tons of comments. But for personal and non-famous bloggers like me, comment moderation is not necessary.