<h1><img class="alignnone size-full wp-image-65" title="Therapulse" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/02/masthead.therapulse.jpg" alt="Therapulse" width="960" height="236" />&nbsp;

Naturepulse: A revolutionary non-invasive technique using  software controlled microvoltage impulses for stimulating tissue, in a  portable, easy to use and affordable system.

&nbsp;</h1>
<img class="size-full wp-image-614 alignleft" title="Naturepulse - 300" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Naturepulse-300.jpg" alt="" width="300" height="195" />Electrical stimulation of tissue brings about the production of natural chemicals  which reduce tissue tension and  inflammation and at the same time  increase the rate of tissue repair.

&nbsp;

The Naturepulse PBK system is a small, portable, rechargeable battery  operated device for home or clinic use that uses software controlled patterns of microvoltages to stimulate            healing processes within damaged tissue. Specific programmes exist for the treatment of specific conditions to accelerate  the natural tissue repair mechanisms.

&nbsp;

Electrodes are placed around the  area of the injury and each programme   is completely built-in to Naturepulse requiring only selection by  simple  push-key operation. The treatment is            more like  acupuncture than electro-therapy.  Impulses are so short-lived             that virtually no current is  generated. Hence Naturepulse PBK does             not operate as  interferrential or TENS-type systems.

&nbsp;

Microvoltages are gathered into programme phases. There may be  as  many as 250 phases in a single 7-minute programme. The effect of the   signals is to reduce tissue tension – a typical feature of injured   tissue. This relaxation phase is associated with reduction of   inflammation in tissue which itself reduces pressure on small blood   vessels.  This greater flow of blood then accelerates delivery of nutrients   to the damaged tissues.

&nbsp;

Variations in amplitude, width and frequency affect the  penetrative depth of the impulses:
<ul>
	<li>Lower frequencies have greater  penetrative depth so that deep muscles, tendons and joints can be  influenced.</li>
	<li>Very high frequencies penetrate only the skin superficial  levels and influence the dermal skin layers and regrowth of cells.</li>
</ul>
As the programme stimulates tissue to react, reinforcement is  required   at regular intervals. Typically, 4-6 treatments are required  over a   period of 10-14 days to see a positive outcome.

&nbsp;
<h2>Naturepulse PBK Therapy AT A Glance</h2>
<ul>
	<li>Quick and easy to use</li>
	<li>Non invasive</li>
	<li>Painless yet exceptionally effective</li>
	<li>Safe to use on most patients</li>
	<li>Patients feel effects quickly</li>
	<li>Relaxes muscle to accelerate healing</li>
	<li>Stimulates anti-inflammatories which reduces pain immediately</li>
	<li>Attacks the cause of the pain, not just the symptoms</li>
	<li>Removes pain for a long time</li>
	<li>Improves muscle strength, mobility and flexibility</li>
	<li>Wide range of applications: Aesthetic, Physiotherapy and Medical</li>
</ul>
<h2>How It Works</h2>
<div>

[caption id="attachment_615" align="alignleft" width="200" caption="VEGF increases after PBK impulse is applied (InVivo: 2005)"]<img class="size-full wp-image-615" title="VEGF Graph" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/VEGF-Graph-200.png" alt="VEGF Graph" width="200" height="133" />[/caption]

Clinical studies[1] have shown that Naturepulse PBK therapy stimulates the natural production of endogenous            Vascular Endothelial Growth Factor (VEGF<a href="http://www.pbkinternational.com/glossary.htm#vegf"></a>)             within blood vessels. This increases blood flow by dilating blood vessels plus the release of a new  micro-circulation in the treatment            area.

&nbsp;

VEGF also stimulates the  release of anti-inflammatory, and therefore pain relieving, Nitric Oxide and Prostacyclin PG12 which act immediately on surrounding tissue. Naturally enhanced blood flow also increases  beneficial oxyhaemoglobin, nutrient and            hormone levels within those tissues.

&nbsp;

Lastly, VEGF stimulates the growth of new blood vessels in that region of the body.  This may take a few days to start but the process begins as soon as the local VEGF is released.<strong> </strong>

</div>
&nbsp;
<div>

&nbsp;
<table border="0">
<tbody>
<tr valign="top">
<td>
<div class="mceTemp">

[caption id="attachment_616" align="alignnone" width="200" caption="Face Toning"]<img class="size-full wp-image-616" title="Face Toning" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Face-toning-2a-4-faces-200.png" alt="Face Toning" width="200" height="192" />[/caption]

<dl id="attachment_590" class="wp-caption alignnone" style="width: 210px;"> <dt class="wp-caption-dt"><img class="size-full wp-image-590" title="Leg Toning" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/legs-200.png" alt="Leg Toning" width="200" height="150" /></dt> <dd class="wp-caption-dd">Leg Toning</dd> </dl></div>
&nbsp;</td>
<td>
<h2>Aesthetic Applications</h2>
Gently applied through tiny electrodes attached to the skin,   Naturepulse PBK provides a revolutionary new approach to electro-therapy using a proven technique designed to stimulate rejuvenation.

&nbsp;

Naturepulse PBK therapy increases the production of the body's natural  chemicals that relax tissue and stimulate repair as well as improving  local microcirculation.

&nbsp;

Specially programmed software controlled electrical impulses improve muscle tone and skin quality in response to oxygenation (TCP02) and other essential natural components to develop a more youthful and toned appearance.

&nbsp;

<strong>Treatments include:</strong>
<ul>
	<li> Facial rejuvenation and improvement of fine lines and wrinkles</li>
	<li>Non-surgical facelift through improved jaw line muscle tension</li>
	<li>General facial skin tone improvement via increased microcirculation</li>
	<li>Upper and lower leg muscle tone improvement affecting leg shapeliness and reduction in cellulite</li>
	<li>Breast firming and toning</li>
	<li>Lip plumping</li>
</ul>
</td>
</tr>
<tr valign="top">
<td><img class="alignnone size-full wp-image-595" title="Muscular Pain Treatment - 200" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Muscular-Pain-Treatment-200.png" alt="" width="200" height="237" /><img class="alignnone size-full wp-image-593" title="Shoulder - 200" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Shoulder-200.png" alt="" width="200" height="150" />

<img class="alignnone size-full wp-image-592" title="Elbow - 200" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Elbow-200.png" alt="" width="200" height="150" /><img class="alignnone size-full wp-image-594" title="Ankle - 200" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Ankle-200.png" alt="" width="200" height="150" /></td>
<td>
<h2>Physiotherapy Applications</h2>
&nbsp;

For the immediate relief of pain caused by acute muscle and joint  pain conditions – the muscle tear on the rugby or football pitch, the  twisting of the knee when skiing, the Achilles tendon problem or frozen  shoulder.

&nbsp;

For chronic conditions, Naturepulse reduces pain associated with  long-term injury and ageing. Use of Naturepulse can reduce the amounts  of pain killers required and is a natural adjunct to the pain budget in  GP practices and recovery clinics.  Naturepulse does not promise  complete recovery from chronic degenerative disease, but is effective at  dealing with the pain aspect associated with the illness.

&nbsp;

Naturepulse:
<ul>
	<li>Accelerates recovery, reducing “on the bench” time</li>
	<li>When used regularly, impacts pain associated with degenerative illnesses such as arthritis</li>
	<li>Is easy to apply and easy to operate</li>
</ul>
<div>·Acute &amp; Chronic pain &amp; injuries</div>
throughout the body such as back, shoulder, lumber, knee, ankle, hands &amp; fingers, foot &amp; toes (locked fingers for example)
<div>·Sports injuries ( treats and speeds up recovery by minimum of 50%)</div>
<div>·Chronic injuries (of any age)</div>
<div>·Age-related conditions due to decrease in function or circulation</div>
<div>·Work-related pain such as RSI, tennis elbow</div></td>
</tr>
<tr valign="top">
<td><img class="alignnone size-full wp-image-575" title="Doctor and Patient" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Doctor-and-patient-200.png" alt="Doctor and Patient" width="200" height="133" />

[caption id="attachment_587" align="alignnone" width="200" caption="Leg Ulcers Before Treatment"]<img class="size-full wp-image-587" title="Leg Ulcers Before Treatment" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Ulcers-Before-200.png" alt="Leg Ulcers Before Treatment" width="200" height="150" />[/caption]

[caption id="attachment_588" align="alignnone" width="200" caption="Leg Ulcers After Treatment"]<img class="size-full wp-image-588" title="Leg Ulcers After Treatment" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Ulcers-After-200.png" alt="Leg Ulcers After Treatment" width="200" height="150" />[/caption]

&nbsp;</td>
<td>
<h2>Medical Applications</h2>
&nbsp;

Under medical supervision, treatment programmes are available to  reduce seriously difficult to treat medical conditions such as diabetic  foot ulceration where  formerly the  only answer was amputation, and  male and female incontinence.  Numerous clinical papers are available  demonstrating the efficacy of this revolutionary treatment
<div>·Diabetic Foot</div>
<div>·Trigeminal Neuralgia</div>
<div>·Orthopaedic conditions</div>
<div>·Neuromuscular rehabilitation</div>
<div>·Dermatological conditions</div>
<div>·Kidney dysfunctions</div>
<div>·Peripheral Neuropathy</div>
<div>·Peripheral Ischemia</div>
<div>·Diabetic Neuropathy</div>
<div>
<div>·Neuro motor Rehabilitation</div>
<div>·Post surgical wound healing</div>
<div>·Retinitis Pigmentosa</div>
<div>·Peripheral Vascular Disease</div>
<div>·Sciatica</div>
<div>·Diabetic Ulcers</div>
<div>·Arthritis (incl. RA and Osteo)</div>
<div>·Skin ulcers</div>
</div></td>
</tr>
</tbody>
</table>
&nbsp;
<h2>FAQs</h2>
<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />What            does the treatment feel like? </strong>
In most cases the feeling is a relatively pleasant sensation. It sometimes            feels like a mild buzzing feeling in your skin but it is never uncomfortable.            The system is designed so you can reduce the overall power to suit your            own sensitivity.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />How            will it affect my day to day activities?</strong>
Will I still be able to work? You can carry on as normal during the            treatment course. It will not affect your usual activities in any way,            except in that you will begin to feel the benefits within three or four            sessions.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />How            many times do I need to come back? </strong>
Depending on the severity and type of your condition you may need to            come back for about ten repeat sessions. This does vary from person            to person but you decide when to stop the treatment – not us.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />How            quickly will I notice an effect? </strong>
Most people notice an improvement within three to four sessions. Again            it depends on the severity of the initial condition, but in many cases            patients have reported total loss of pain within eight to ten sessions.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />Do            I need to stay on my medication?</strong>
That is entirely up to you but you should seek your own GP's advice.            Many previous patients have stopped taking their pain-killing medication            simply because they did not need them!

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />If            the PBK System is used twice in quick succession on a patient area will            it have a detrimental effect? </strong>
No. However, clinical evidence shown that treatments are more efficient            if we leave at least two hours between two successive sessions on the            same tissue area.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />What            do you find are the key selling points?</strong>
Quick effect, easy to use, a lot of indications and almost no contraindications.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />What            has the feedback been from the users of the devices?</strong>
Positive impression, the effect for about 70% of patients.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />Has            there been any other devices that have tried to compete with this device?</strong>
No.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />Have            your customers been reporting success with treatments and decreased            healing time?</strong>
Usually you can see the effect after 5-10 sessions, that means in 7            - 10 days.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />What            type of diseases or ailments have your customers been treating?</strong>
All kinds of pains, all kinds of vascular pathology, microcirculation,            joints.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />Have            the Doctors and Physiotherapists been happy with the integration of            the PBK System into there daily practices?</strong>
Yes.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />Is            the machine easy to use?</strong>
Yes. One training day was enough for our staff.

&nbsp;

</div>
&nbsp;
<h2>Scientific Research</h2>
Clinical studies[1] have shown that microvoltage stimulation increases VEGF,  Nitric Oxide and  Prostacylins – chemical complexes that reduce  inflammation, relax  tissue and improve blood flow through tissue.

&nbsp;
<table border="0">
<tbody>
<tr valign="top">
<td><img class="alignnone size-full wp-image-582" title="Blood Vessels" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Blood-Vessels-200.png" alt="Blood Vessels" width="200" height="143" /></td>
<td style="padding-left: 20px;"><strong>VEGF - Vascular Endothelial Growth Factor</strong>
A  cytokine which has a variety of actions in the clotting of blood and             in controlling blood pressure - it can be used as treatment to  treat            diseases such as heart attack and stroke i.e. areas of  ischaemia.&nbsp;

<strong>
</strong>

VEGF can promote angiogenesis (the development of new  blood vessels)              - important in areas that are blocked i.e.  the heart or the brain              etc. Therefore electrical  stimulation can locally up-regulate VEGF,              previously  demonstrated in the rat model on hind limb ischaemia (when               an organ like the heart or brain does not receive enough oxygen thru               the blood).</td>
</tr>
</tbody>
</table>
P.Ferroni et al of the Department of Experimental Medicine and Pathology, University of La Sapienza, Rome, demonstrated that patients with blocked arteries due to ulcers who underwent electrical stimulation with Naturepulse (formerly called PBK) treatment showed:
<ul>
	<li>No indication              of adverse effects i.e. blood clotting or inflammation</li>
	<li>Both serum and              plasma showed an increase in VEGF accompanied by an increase in TNFa              and ILß only</li>
	<li>Circulation of beneficial Nitric              Oxide levels increased</li>
</ul>
The study proved that the Naturepulse system works on a molecular level by              stimulating the release of a range of endogenous activators within              various tissues. Most importantly, the localised release of VEGF has              been clearly demonstrated in the laboratory.              The results of this study were presented to the CE test board as part              of the approval process. Current directives stipulate that scientific              evidence must back-up clinical data to satisfy the CE mark requirements.              Through this study the Naturepulse/PBK system demonstrated the scientific basis              of the clinical claims with ease.

&nbsp;

References:
<table border="0">
<tbody>
<tr>
<td style="padding-right: 20px;"><a href="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/04/InVivo.pdf" target="_blank"><img class="alignnone" title="PDF Logo" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/02/pdf-logo1.jpeg" alt="PDF Logo" width="31" height="33" /></a></td>
<td>[1] <a title="In Vivo" href="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/04/InVivo.pdf" target="_blank">P.Ferroni et al (2005)</a>.   <strong> </strong> <strong> </strong><strong>
</strong>Biological Effects of a Software-controlled Voltage Pulse                  Generator (PBK-2C) on the Release of Vascular Endothelial Growth                  Factor (VEGF). In Vivo 19: 949-958                  (2005).</td>
</tr>
</tbody>
</table>