<h1><img class="alignnone size-full wp-image-65" title="Therapulse" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/02/masthead.therapulse.jpg" alt="Therapulse" width="960" height="236" />&nbsp;

Naturepulse: A revolutionary non-invasive technique using  software controlled microvoltage impulses for stimulating tissue, in a  portable, easy to use and affordable system.

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Electrical stimulation of tissue brings about the production of natural chemicals  which reduce tissue tension and  inflammation and at the same time  increase the rate of tissue repair. Naturepulse uses programmed patterns of microvoltages, created for the treatment of specific conditions to improve micro-circulation in the treated areas, allowing more nutrients to  be brought to the treatment site.

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The microvoltages are of such short wavelength no current is  created.  Variations in amplitude, width and frequency affect the  penetrative depth of the impulses:
<ul>
	<li>Lower frequencies have greater  penetrative depth so that deep muscles, tendons and joints can be  influenced.</li>
	<li>Very high frequencies penetrate only the skin superficial  levels and influence the dermal skin layers and regrowth of cells.</li>
</ul>
Microvoltages are gathered into programme phases and there may be  as many as 250 phases in a single 7-minute programme. The effect of the  signals is to reduce tissue tension – a typical feature of injured  tissue. This relaxation phase is associated with reduction of  inflammation in tissue which itself reduces pressure on small blood  vessels.  This greater flow of blood accelerates delivery of nutrients  to the damaged tissues.  Clinical measurements [1] In Vivo: 2005, indicate  quite clearly that application of the microvoltage signal increases VEGF,  Nitric Oxide and Prostacylins – chemical complexes that reduce  inflammation, relax tissue and improve blood flow through tissue.
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<div><img class="alignleft size-full wp-image-66" style="margin-right: 30px; margin-bottom: 70px;" title="Therapulse from appearanceskincare" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/02/therapulse1.jpg" alt="Therapulse from appearanceskincare" width="148" height="99" /></div></td>
<td>Naturepulse is a small, portable, rechargeable battery  operated device for home or clinic use.&nbsp;

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Electrodes are placed around the  area of the injury and each programme is completely built-in to Naturepulse requiring only selection by simple push-key operation.

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As the programme stimulates tissue to react, reinforcement is  required at regular intervals. Typically, 4-6 treatments are required  over a period of 10-14 days to see a positive outcome.

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Long term  chronic illnesses require regular treatments to control pain.</td>
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[caption id="attachment_562" align="alignnone" width="150" caption="Facial Toning"]<a href="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/04/Face-toning-1a.png"><img class="size-full wp-image-562 " title="Facial Toning" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Face-toning-1-150.png" alt="Facial Toning" width="150" height="254" /></a>[/caption]</td>
<td><strong>Cosmetic Applications</strong>&nbsp;

Gently applied through tiny electrodes attached to the skin,  Naturepulse provides programmes for improving muscle tone and blood  circulation.

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Applications include:
<ul>
	<li>Facial tissue tightening and jowel reduction. As age progresses, skin collagen relaxes and reduces. Body muscle     mass loses its tone. Therapulse reduces wrinkles around the eyes,     plumps lips and improves skin to give a more youthful and toned facial     profile - A truly non-surgical facelift!</li>
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	<li>Applied to the legs, the impulses improve muscle tone affecting shapeliness and reducing cellulite</li>
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[caption id="attachment_571" align="alignnone" width="150" caption="Muscular Pain Treatment"]<a href="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/04/Muscular-Pain-Treatment.png"><img class="size-full wp-image-571" title="Muscular Pain Treatment" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/04/Muscular-Pain-Treatment-150.png" alt="Muscular Pain Treatment" width="150" height="178" /></a>[/caption]

<img class="alignnone size-full wp-image-576" title="Sore Ankle" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Sore-Ankle-200.png" alt="Sore Ankle" width="200" height="267" /></td>
<td style="padding-left: 20px;"><strong>Physiotherapy Applications
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For the immediate relief of pain caused by acute muscle and joint  pain conditions – the muscle tear on the rugby or football pitch, the  twisting of the knee when skiing, the Achilles tendon problem or frozen  shoulder.

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For chronic conditions, Naturepulse reduces pain associated with  long-term injury and ageing. Use of Naturepulse can reduce the amounts  of pain killers required and is a natural adjunct to the pain budget in  GP practices and recovery clinics.  Naturepulse does not promise  complete recovery from chronic degenerative disease, but is effective at  dealing with the pain aspect associated with the illness.

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Naturepulse:
<ul>
	<li>Accelerates recovery, reducing “on the bench” time</li>
	<li>When used regularly, impacts pain associated with degenerative illnesses such as arthritis</li>
	<li>Is easy to apply and easy to operate</li>
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<td><img class="alignnone size-full wp-image-575" title="Doctor and Patient" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Doctor-and-patient-200.png" alt="Doctor and Patient" width="200" height="133" /></td>
<td style="padding-left: 30px;"><strong>Medical Applications
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Under medical supervision, treatment programmes are available to  reduce seriously difficult to treat medical conditions such as diabetic  foot ulceration where  formerly the  only answer was amputation, and  male and female incontinence.  Numerous clinical papers are available  demonstrating the efficacy of this revolutionary treatment</td>
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<h2>FAQs</h2>
<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />What            does the treatment feel like? </strong>
In most cases the feeling is a relatively pleasant sensation. It sometimes            feels like a mild buzzing feeling in your skin but it is never uncomfortable.            The system is designed so you can reduce the overall power to suit your            own sensitivity.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />How            will it affect my day to day activities?</strong>
Will I still be able to work? You can carry on as normal during the            treatment course. It will not affect your usual activities in any way,            except in that you will begin to feel the benefits within three or four            sessions.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />How            many times do I need to come back? </strong>
Depending on the severity and type of your condition you may need to            come back for about ten repeat sessions. This does vary from person            to person but you decide when to stop the treatment – not us.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />How            quickly will I notice an effect? </strong>
Most people notice an improvement within three to four sessions. Again            it depends on the severity of the initial condition, but in many cases            patients have reported total loss of pain within eight to ten sessions.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />Do            I need to stay on my medication?</strong>
That is entirely up to you but you should seek your own GP's advice.            Many previous patients have stopped taking their pain-killing medication            simply because they did not need them!

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />If            the PBK System is used twice in quick succession on a patient area will            it have a detrimental effect? </strong>
No. However, clinical evidence shown that treatments are more efficient            if we leave at least two hours between two successive sessions on the            same tissue area.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />What            do you find are the key selling points?</strong>
Quick effect, easy to use, a lot of indications and almost no contraindications.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />What            has the feedback been from the users of the devices?</strong>
Positive impression, the effect for about 70% of patients.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />Has            there been any other devices that have tried to compete with this device?</strong>
No.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />Have            your customers been reporting success with treatments and decreased            healing time?</strong>
Usually you can see the effect after 5-10 sessions, that means in 7            - 10 days.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />What            type of diseases or ailments have your customers been treating?</strong>
All kinds of pains, all kinds of vascular pathology, microcirculation,            joints.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />Have            the Doctors and Physiotherapists been happy with the integration of            the PBK System into there daily practices?</strong>
Yes.

<strong><img src="http://www.pbkinternational.com/phy_imgs/aarrow_red1.gif" alt="" width="12" height="7" />Is            the machine easy to use?</strong>
Yes. One training day was enough for our staff.

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<h2>Scientific Research</h2>
Clinical studies[1] have shown that microvoltage stimulation increases VEGF,  Nitric Oxide and  Prostacylins – chemical complexes that reduce  inflammation, relax  tissue and improve blood flow through tissue.

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<td><img class="alignnone size-full wp-image-582" title="Blood Vessels" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/03/Blood-Vessels-200.png" alt="Blood Vessels" width="200" height="143" /></td>
<td style="padding-left: 20px;"><strong>VEGF - Vascular Endothelial Growth Factor</strong>
A  cytokine which has a variety of actions in the clotting of blood and             in controlling blood pressure - it can be used as treatment to  treat            diseases such as heart attack and stroke i.e. areas of  ischaemia.&nbsp;

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VEGF can promote angiogenesis (the development of new  blood vessels)              - important in areas that are blocked i.e.  the heart or the brain              etc. Therefore electrical  stimulation can locally up-regulate VEGF,              previously  demonstrated in the rat model on hind limb ischaemia (when               an organ like the heart or brain does not receive enough oxygen thru               the blood).</td>
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P.Ferroni et al of the Department of Experimental Medicine and Pathology, University of La Sapienza, Rome, demonstrated that patients with blocked arteries due to ulcers who underwent electrical stimulation with Naturepulse (formerly called PBK) treatment showed:
<ul>
	<li>No indication              of adverse effects i.e. blood clotting or inflammation</li>
	<li>Both serum and              plasma showed an increase in VEGF accompanied by an increase in TNFa              and ILß only</li>
	<li>Circulation of beneficial Nitric              Oxide levels increased</li>
</ul>
The study proved that the Naturepulse system works on a molecular level by              stimulating the release of a range of endogenous activators within              various tissues. Most importantly, the localised release of VEGF has              been clearly demonstrated in the laboratory.              The results of this study were presented to the CE test board as part              of the approval process. Current directives stipulate that scientific              evidence must back-up clinical data to satisfy the CE mark requirements.              Through this study the Naturepulse/PBK system demonstrated the scientific basis              of the clinical claims with ease.

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References:
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<td style="padding-right: 20px;"><a href="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/04/InVivo.pdf" target="_blank"><img class="alignnone" title="PDF Logo" src="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/02/pdf-logo1.jpeg" alt="PDF Logo" width="31" height="33" /></a></td>
<td>[1] <a title="In Vivo" href="http://www.cosmeticmedicaltechnologies.com/wp-content/uploads/2011/04/InVivo.pdf" target="_blank">P.Ferroni et al (2005)</a>.   <strong> </strong> <strong> </strong><strong>
</strong>Biological Effects of a Software-controlled Voltage Pulse                  Generator (PBK-2C) on the Release of Vascular Endothelial Growth                  Factor (VEGF). In Vivo 19: 949-958                  (2005).</td>
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